Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis when overexpressed
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Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis when overexpressedAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the
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