PTEN Monoclonal Antibody, 50ul Site-directed Mutagenesis Together with metastasis-associated protein-2

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PTEN Monoclonal Antibody, 50ul Site-directed Mutagenesis Together with metastasis-associated protein-2This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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