RhoGEF p115 Polyclonal Antibody, 50ul Cell Culture Dishes The protein is a component

The protein is a component of multiple complexes

This gene is thought to be associated with gastric cancer

|PTM:During G0 and early G1 phase of the cell cycle| phosphorylated on Ser-639 and on 5 sites within the domain B

Contains 1 PFU domain

RhoGEF p115 Polyclonal Antibody, 50ul Cell Culture Dishes The protein is a componentRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The rho guanine nucleotide exchange factor 1 may form complex with G proteins and stimulate Rho dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full length nature of some variants has not been defined.