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GBX2 Polyclonal Antibody, 100ul In vitro Assessment This gene is significantly upregulated

SKU: 32631409696

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GBX2 Polyclonal Antibody, 100ul In vitro Assessment This gene is significantly upregulated

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

This gene is significantly upregulated in Fanconi's anemia fibroblasts but downregulated or absent in fibroblasts from normal donors

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF

Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins

This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription

GBX2 Polyclonal Antibody, 100ul In vitro Assessment This gene is significantly upregulated

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