IRF3 Polyclonal Antibody, 50ul Cell Senescence This gene is a member

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12

This gene encodes a complex glycoprotein secreted in plasma

along with desmogleins

Defects in this gene cause X-linked Opitz-Kaveggia syndrome

IRF3 Polyclonal Antibody, 50ul Cell Senescence This gene is a memberIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed