EWS Polyclonal Antibody, 100ul Cryogenic Vials Spastic paraplegias are a diverse

Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive| lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts

This protein is assembled into a nucleoprotein complex that is involved in the repair of DNA lesions

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This locus may represent a gene involved in regulation of transcription elongation and chromatin remodeling| based on studies of similar proteins in other organisms

EWS Polyclonal Antibody, 100ul Cryogenic Vials Spastic paraplegias are a diverseEWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N terminal transcriptional activation domain and a C terminal RNA binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These