WASP Polyclonal Antibody, 50ul Dry Bath This I-domain containing alpha integrin

This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1)

The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus

a B-box type 1 and a B-box type 2 - and a coiled-coil region

Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability

WASP Polyclonal Antibody, 50ul Dry Bath This I-domain containing alpha integrinThe Wiskott Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase,