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SPP2A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation An important paralog of this

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SPP2A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation An important paralog of thisThis gene encodes a member of the GXGD family of aspartic proteases which are transmembrane proteins with two conserved catalytic motifs localized within the membrane spanning regions as well as a member of the signal peptide peptidase like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.

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Description

An important paralog of this gene is MID1

The protein localizes to centrosomes during interphase

52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al

but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC

SPP2A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation An important paralog of thisThis gene encodes a member of the GXGD family of aspartic proteases which are transmembrane proteins with two conserved catalytic motifs localized within the membrane spanning regions as well as a member of the signal peptide peptidase like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.

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