MARK2 Polyclonal Antibody, 100ul[BT-AP05230] Peptide Modification MDM2 encodes a nuclear-localized E3

MDM2 encodes a nuclear-localized E3 ubiquitin ligase

It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation

A functional role of this protein is unclear

may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules

MARK2 Polyclonal Antibody, 100ul[BT-AP05230] Peptide Modification MDM2 encodes a nuclear-localized E3MARK2 encodes a member of the Par 1 family of serine threonine protein kinases. Serine threonine protein kinase MARK2 is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this