Catenin-Beta Polyclonal Antibody, 100ul[BT-AP01226] Low retention tips The filaggrin-like protein encoded by

The filaggrin-like protein encoded by this gene is upregulated by calcium| proteolyzed by calpain 1| and is involved in epithelial homeostasis

This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA

This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif

The encoded protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein

Catenin-Beta Polyclonal Antibody, 100ul[BT-AP01226] Low retention tips The filaggrin-like protein encoded byThe protein (catenin beta 1) encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.