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GPER Polyclonal Antibody, 100ul Electrophoresis & Labeling Functioning as a classical cadherin

SKU: 36656052815

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GPER Polyclonal Antibody, 100ul Electrophoresis & Labeling Functioning as a classical cadherinThis gene is a member of the G protein coupled receptor 1 family and encodes a multi pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5 trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen.

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Description

Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters

and is implicated in the processes of cell adhesion and migration

Hyperglycemia increases the levels of diacylglycerol| which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia

GPER Polyclonal Antibody, 100ul Electrophoresis & Labeling Functioning as a classical cadherinThis gene is a member of the G protein coupled receptor 1 family and encodes a multi pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5 trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen.

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