LDOC1 Polyclonal Antibody, 100ul Vessels RBX1 and VHL
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LDOC1 Polyclonal Antibody, 100ul Vessels RBX1 and VHLThe leucine zipper down regulated in cancer 1 encoded by LDOC1 contains a leucine zipper like motif and a proline rich region that shares marked similarity with an SH3 binding domain. The protein localizes to the nucleus and is down regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF kappaB). The gene has been proposed as a tumor suppressor gene whose protein product
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