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CLCN5 Polyclonal Antibody, 20ul Vortex Mixer It coimmunoprecipitates only with HDAC3

SKU: 38622778696

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PLN85.00 PLN115.00

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CLCN5 Polyclonal Antibody, 20ul Vortex Mixer It coimmunoprecipitates only with HDAC3This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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Description

It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins

and also as a coactivator of NF-kappaB-mediated transcription

and overexpressed in colon tumors

These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons

CLCN5 Polyclonal Antibody, 20ul Vortex Mixer It coimmunoprecipitates only with HDAC3This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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