TPP1 Polyclonal Antibody, 50ul Dry Bath Overexpression of this gene leads
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TPP1 Polyclonal Antibody, 50ul Dry Bath Overexpression of this gene leadsThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific
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