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TPP1 Polyclonal Antibody, 50ul Dry Bath Overexpression of this gene leads

SKU: 39018558330

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TPP1 Polyclonal Antibody, 50ul Dry Bath Overexpression of this gene leadsThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific

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Description

Overexpression of this gene leads to elevated expression of several GADD family genes

Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms

and may play a critical role in glutathione homeostasis

but also towards 2

TPP1 Polyclonal Antibody, 50ul Dry Bath Overexpression of this gene leadsThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific

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