Dab1(Phospho Tyr220) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser SERPINE1 encodes a member of

SERPINE1 encodes a member of the serine proteinase inhibitor (serpin) superfamily

which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al

The beta chain is approximately 26-28 kDa and its gene contains 6 exons

and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis

Dab1(Phospho Tyr220) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser SERPINE1 encodes a member ofThe PID domain specifically binds to the Asn Pro Xaa Tyr(P) motif found in many tyrosine phosphorylated proteins. Adapter molecule functioning in neural development. May regulate SIAH1 activity. PTM: Phosphorylated on Tyr 198 and Tyr 220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser 524 independently of reelin signaling. Contains 1 PID domain. subunit: Associates with the SH2 domains of SRC FYN and ABL.