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RNF24 Rabbit Polyclonal Antibody, 50ul Sampling Tubes Transition protein-1 is a spermatid-specific

SKU: 39574715987

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RNF24 Rabbit Polyclonal Antibody, 50ul Sampling Tubes Transition protein-1 is a spermatid-specific

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1| MIM 182880

Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E)

The CARD domains of both proteins have been shown to specifically interact with BCL10| a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation

This gene may also play a role in tumor progression

RNF24 Rabbit Polyclonal Antibody, 50ul Sampling Tubes Transition protein-1 is a spermatid-specific

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