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TIS11B(Phospho Ser92) Polyclonal Antibody, 20ul Vortex Mixer Pyruvate dehydrogenase kinase 2 phosphorylates

SKU: 3969948175

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DKK97.20 DKK119.20

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TIS11B(Phospho Ser92) Polyclonal Antibody, 20ul Vortex Mixer Pyruvate dehydrogenase kinase 2 phosphorylatesThis gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys his motif. This putative nuclear transcription factor most likely

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Description

Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase

where it participates in the export of mRNA from the nucleus

Mutations in this gene are associated with a variety of human cancers

The encoded protein localizes to centrosomes and microtubules| and associates with the GTP-activated forms of Ras| Rap1| and several other Ras-like small GTPases

TIS11B(Phospho Ser92) Polyclonal Antibody, 20ul Vortex Mixer Pyruvate dehydrogenase kinase 2 phosphorylatesThis gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys his motif. This putative nuclear transcription factor most likely

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