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MITF Polyclonal Antibody, 50ul Glassware Sets The encoded protein is an

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MITF Polyclonal Antibody, 50ul Glassware Sets The encoded protein is anMITF encodes microphthalmia associated transcription factor that contains both basic helix loop helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz

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Description

The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm

The encoded protein is highly basic| contains a PAZ domain and a PIWI domain| and may play a role in short-interfering-RNA-mediated gene silencing

subunit:Self-associates and interacts with EIF3 p170 subunit

This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance

MITF Polyclonal Antibody, 50ul Glassware Sets The encoded protein is anMITF encodes microphthalmia associated transcription factor that contains both basic helix loop helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz

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