TBCD7 Rabbit Polyclonal Antibody, 100ul Centrifuges ThAKAP8 encodes a nuclear A-kinase

ThAKAP8 encodes a nuclear A-kinase anchor protein (A-kinase anchoring protein 8) that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin

This transmembrane protein localizes to the endoplasmic reticulum of many tissues

MDM2 is itself transcriptionally-regulated by p53

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development

TBCD7 Rabbit Polyclonal Antibody, 100ul Centrifuges ThAKAP8 encodes a nuclear A-kinaseThis gene encodes a member of the TBC domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1 TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus