ABHDD Polyclonal Antibody, 50ul Peptide Modification Mitochondrial translation is crucial for

Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA

Eight transcript variants encoding the same protein have been found for this gene

DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus

The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex

ABHDD Polyclonal Antibody, 50ul Peptide Modification Mitochondrial translation is crucial forsequence Translated as Leu. Belongs to the serine esterase family.