RN123 Polyclonal Antibody, 50ul Antibody Development The product of this gene

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules

Contains 1 DENN domain

Mutations in NODAL are associated with heterotaxy

Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation

RN123 Polyclonal Antibody, 50ul Antibody Development The product of this geneThe protein encoded by this gene contains a C terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein protein and protein DNA interactions, and an N terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants.