SNX1 Polyclonal Antibody, 100ul Biomatrix This gene encodes the 85

This gene encodes the 85 kD regulatory subunit

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds

Mutations in this gene cause Wolf-Hirschhorn syndrome| a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4

subunit:Interacts with DERL2 and DERL3

SNX1 Polyclonal Antibody, 100ul Biomatrix This gene encodes the 85SNX1 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Sorting nexin 1 regulates the cell surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease activated receptor 1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members.