NKp30 Polyclonal Antibody, 50ul[BT-AP06044] Inoculating Loops/Needles The type II isozyme

The type II isozyme

immune-mediated inflammatory diseases and feeding regulation

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

The gene is part of a cluster of serine protease genes on chromosome 16

NKp30 Polyclonal Antibody, 50ul[BT-AP06044] Inoculating Loops/Needles The type II isozymeThe natural cytotoxicity triggering receptor 3 encoded by NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3 zeta (CD247), a T cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.