ARAP1 Polyclonal Antibody, 100ul Immunology The beta subunit is the

The beta subunit is the same in both the muscle and hepatic isoforms

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5|10-methylene tetrahydrofolate

Mutations in this gene are associated with hypogonadotropic hypogonadism

and more selectively in adult tissues

ARAP1 Polyclonal Antibody, 100ul Immunology The beta subunit is theThe protein encoded by this gene contains SAM, ARF GAP, RHO GAP, ankyrin repeat, RAS associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) dependent ARF GAP activity. The encoded protein associates with the Golgi, and the ARF GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell specific trafficking of a