IBP4 Polyclonal Antibody, 100ul Culture Media an autosomal recessive disorder characterized

an autosomal recessive disorder characterized by unregulated insulin secretion

The protein encoded by RREB1 (ras responsive element binding protein 1) is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters

Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6)

Three transcript variants| one protein-coding and the other two non-protein coding| have been found for this gene

IBP4 Polyclonal Antibody, 100ul Culture Media an autosomal recessive disorder characterizedThis gene is a member of the insulin like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type I domain. The protein binds both insulin like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non glycosylated forms. Binding of this protein prolongs the half life of the IGFs and alters their interaction with cell surface receptors.