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BCoR Polyclonal Antibody, 100ul Liquid Handling &Storage tumor suppressor mediated growth arrest

SKU: 4465638428

4.2
PLN141.00 PLN166.00

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BCoR Polyclonal Antibody, 100ul Liquid Handling &Storage tumor suppressor mediated growth arrestThe protein (BCL6 corepressor) encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link

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Description

tumor suppressor mediated growth arrest and replicative senescence

GO annotations related to this gene include hydrolase activity and serine-type peptidase activity

Binding occurs as a ternary complex of methionyl-tRNA

This protein also regulates NFAT and AP-1

BCoR Polyclonal Antibody, 100ul Liquid Handling &Storage tumor suppressor mediated growth arrestThe protein (BCL6 corepressor) encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link

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