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Raf-1(Phospho Ser642) Polyclonal Antibody, 50ul sgRNA customized design This protein is an IgE

SKU: 45230972431

4.1
USD142.00 USD183.00

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Raf-1(Phospho Ser642) Polyclonal Antibody, 50ul sgRNA customized design This protein is an IgEThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

This protein is an IgE autoantigen in atopic dermatitis patients

Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus

The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein

Raf-1(Phospho Ser642) Polyclonal Antibody, 50ul sgRNA customized design This protein is an IgEThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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