Nanog P8 Polyclonal Antibody, 50ul Centrifugal Filter Several transcript variants encoding distinct

Several transcript variants encoding distinct isoforms have been identified for this gene

This gene encodes a member of the Polycomb-group (PcG) family

Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene

subcellular location:Associated with perinuclear vesicles

Nanog P8 Polyclonal Antibody, 50ul Centrifugal Filter Several transcript variants encoding distinctThis locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a