Mouse Coiled-coil Domain-containing Protein 134, CCDC134 ELISA Kit , 96T Cell Transfection subunit:Homodimer

subunit:Homodimer

The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway

This cytokine functions by binding to its receptor

Participates also in immunologic synapse formation (PubMed: 27405666)

Mouse Coiled-coil Domain-containing Protein 134, CCDC134 ELISA Kit , 96T Cell Transfection subunit:HomodimerIn extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine like function. Enhances cytotoxic anti tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling. In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF mediated