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Survivin Polyclonal Antibody, 50ul[BT-AP14595] Oligo Pool CAGE (cancer-associated gene protein)

SKU: 45654437872

4.4
USD162.00 USD182.00

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Survivin Polyclonal Antibody, 50ul[BT-AP14595] Oligo Pool CAGE (cancer-associated gene protein)This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.

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Description

CAGE (cancer-associated gene protein)

is required for efficient activation by SP1

Multiple phosphorylation sites have been identified: ser297 and Ser392 mediate 14-3-3 binding

ATP5J2 has multiple pseudogenes

Survivin Polyclonal Antibody, 50ul[BT-AP14595] Oligo Pool CAGE (cancer-associated gene protein)This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.

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