BIG2 Polyclonal Antibody, 100ul Purification The encoded protein mediates cell

The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup

The predicted 727-amino acid human protein contains a 29-amino acid presequence

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The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix

BIG2 Polyclonal Antibody, 100ul Purification The encoded protein mediates cellADP ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein (ADP ribosylation factor guanine nucleotide exchange factor 2) encoded by ARFGEF2 is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine nucleotide exchange activity and also brefeldin A inhibition.