IL-12A Polyclonal Antibody, 100ul Bottle-Top Dispenser The pleiotropic biologic activities of

The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas

A related pseudogene has been identified on chromosome 4

High level expression of CCND2 was observed in ovarian and testicular tumors

but another polymorphism has been associated with increased plasma cholesterol levels

IL-12A Polyclonal Antibody, 100ul Bottle-Top Dispenser The pleiotropic biologic activities ofIL12A encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide linked heterodimer composed of the 35 kD subunit encoded by this gene, and a 40 kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T cell independent induction of interferon (IFN) gamma, and is important for the differentiation of both Th1 and Th2 cells.