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Desmin Monoclonal Antibody, 100ul Virus Packaging tissue specificity:Expressed at highest levels

SKU: 47816223668

4.1
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Desmin Monoclonal Antibody, 100ul Virus Packaging tissue specificity:Expressed at highest levelsThis gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

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Description

tissue specificity:Expressed at highest levels in brain

At least three alternatively spliced transcript variants encoding the same protein have been reported

It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders

Subunit A associates with a tight dimer composed of the B and C subunits

Desmin Monoclonal Antibody, 100ul Virus Packaging tissue specificity:Expressed at highest levelsThis gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

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