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LRAT Polyclonal Antibody, 20ul Drug Development and Evaluation Expression of ADCK2 inversely correlates

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LRAT Polyclonal Antibody, 20ul Drug Development and Evaluation Expression of ADCK2 inversely correlatesLecithin retinol acyltransferase encoded by LRAT localizes to the endoplasmic reticulum, where it catalyzes the esterification of all trans retinol into all trans retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

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Description

Expression of ADCK2 inversely correlates with cellular viability

1 Units/μL of yeast-based activity in a convenient 500 μL package

The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3)

It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein

LRAT Polyclonal Antibody, 20ul Drug Development and Evaluation Expression of ADCK2 inversely correlatesLecithin retinol acyltransferase encoded by LRAT localizes to the endoplasmic reticulum, where it catalyzes the esterification of all trans retinol into all trans retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

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