CP27B Polyclonal Antibody, 20ul Glassware Sets The tripartite motif containing 16

The tripartite motif containing 16 encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family

Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases

The protein encoded by CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1) is a member of the methylthiotransferase family

The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex

CP27B Polyclonal Antibody, 20ul Glassware Sets The tripartite motif containing 16This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25 hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25 dihydroxyvitamin D3, the active form