MOB1(Phospho-Thr12) Rabbit Polyclonal Antibody, 20ul Long RNA Synthesis tissue specificity:Widely expressed

tissue specificity:Widely expressed

Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway| thereby allowing activation and nuclear translocation of the NFKB complex

This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane

and is a member of a small gene family

MOB1(Phospho-Thr12) Rabbit Polyclonal Antibody, 20ul Long RNA Synthesis tissue specificity:Widely expressedThe protein encoded by this gene is a component of the Hippo signaling pathway which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.