HLAG Polyclonal Antibody, 50ul Molecular Biology This gene has a paralog

This gene has a paralog located in the nonrecombining region of the Y chromosome

Alternative splicing yields two isoforms that differ in abundance and expression patterns

Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis

The encoded protein| which functions as a repressor| may play a role in brain development

HLAG Polyclonal Antibody, 50ul Molecular Biology This gene has a paralogHLA G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide,