PKC theta(Phospho Ser676) Polyclonal Antibody, 100ul Modified Oligos Overexpression of Dok-4 is associated

Overexpression of Dok-4 is associated with clear cell renal cell carcinoma

cofactor:Binds 1 calcium ion per subunit

The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils

Two transcript variants encoding the same protein have been found for this gene

PKC theta(Phospho Ser676) Polyclonal Antibody, 100ul Modified Oligos Overexpression of Dok-4 is associatedProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile