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MIB1 Polyclonal Antibody, 100ul Modified Oligos In nonmuscle cells| the cytoskeletal

SKU: 48950548103

4.4
PLN123.75 PLN165.75

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MIB1 Polyclonal Antibody, 100ul Modified Oligos In nonmuscle cells| the cytoskeletalMIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death associated protein kinase 1 (DAPK1).

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Description

In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane

whereby it binds complement C8 and/or C9 during the assembly of this complex

A pseudogene has been identified on chromosome Y

This protein forms a trimeric complex with cyclin H and MAT2

MIB1 Polyclonal Antibody, 100ul Modified Oligos In nonmuscle cells| the cytoskeletalMIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death associated protein kinase 1 (DAPK1).

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