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FAK(Phospho Tyr407) Polyclonal Antibody, 20ul Nucleic Acid Amplification Expansion of a polyalanine repeat

SKU: 49211857019

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FAK(Phospho Tyr407) Polyclonal Antibody, 20ul Nucleic Acid Amplification Expansion of a polyalanine repeatThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

Expansion of a polyalanine repeat region and other mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3

Nuclear factor NF-kappa-B p50 subunit interacts with NFKBID

and it can promote cell survival in prostate cancer

MSTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

FAK(Phospho Tyr407) Polyclonal Antibody, 20ul Nucleic Acid Amplification Expansion of a polyalanine repeatThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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