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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture It heterodimerizes with asparagine-linked glycosylation

SKU: 49318005994

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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture It heterodimerizes with asparagine-linked glycosylationBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation

Inhibitors of the encoded protein may be effective in treating congestive heart failure

Mutations in this gene result in multiple epiphyseal dysplasia

Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes

BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture It heterodimerizes with asparagine-linked glycosylationBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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