PLC Gamma1 Polyclonal Antibody, 50ul[BT-AP07261] Serum & Sample Tubes GTP cyclohydrolase I feedback regulatory

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I

or protein kinase C activation

This protein is associated with double-strand break repair of DNA damage caused by radiation

phosphorylation and polyubiquitination

PLC Gamma1 Polyclonal Antibody, 50ul[BT-AP07261] Serum & Sample Tubes GTP cyclohydrolase I feedback regulatoryPhospholipase C gamma 1 encoded by PLCG1 catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, phospholipase C gamma 1 causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the