DAAM1 Polyclonal Antibody, 100ul Nucleic Acid Extraction MELK (Maternal Embryonic Leucine Zipper

MELK (Maternal Embryonic Leucine Zipper Kinase) is a Protein Coding gene

This gene is closely linked with two other apolipoprotein genes on chromosome 11

Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease)

The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme

DAAM1 Polyclonal Antibody, 100ul Nucleic Acid Extraction MELK (Maternal Embryonic Leucine ZipperCell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt