AP-1 Polyclonal Antibody, 50ul[BT-AP00487] Reagent Reservoirs The encoded preproprotein is proteolytically

The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide

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Associates with replicating mitochondria

The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation

AP-1 Polyclonal Antibody, 50ul[BT-AP00487] Reagent Reservoirs The encoded preproprotein is proteolyticallyJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.