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SLP-76 Polyclonal Antibody, 20ul[BT-AP08367] Hybridoma Antibody Sequencing ELL is an elongation factor

SKU: 50427145590

4.6
SEK97.20 SEK121.20

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SLP-76 Polyclonal Antibody, 20ul[BT-AP08367] Hybridoma Antibody Sequencing ELL is an elongation factorSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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Description

ELL is an elongation factor that inrecase the catalytic rate of RNA polymerase II transcription via suppressing transient pausing by the polymerase at multiple sites along the DNA

the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa

May be involved in cell-adhesion

and its gene mutation and increased expression may be associated with human cancer

SLP-76 Polyclonal Antibody, 20ul[BT-AP08367] Hybridoma Antibody Sequencing ELL is an elongation factorSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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