Human Serine Threonine-protein Phosphatase PP1-alpha Catalytic Subunit, PPP1CA ELISA Kit, 96T Site-directed Mutagenesis Downregulation of expression of this

Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies

AKAP11 encodes a member of the AKAP family

This gene encodes a protein that contains a WD-40 domain| and is thought to be involved in diphthamide biosynthesis

Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome (PubMed: 15147878)

Human Serine Threonine-protein Phosphatase PP1-alpha Catalytic Subunit, PPP1CA ELISA Kit, 96T Site-directed Mutagenesis Downregulation of expression of this