Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos This protein is involved in

This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity

PEAK1 (pseudopodium enriched atypical kinase 1) encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family

Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex

This gene has been found fused to a variety of translocation partner genes in various leukemias| most notably the t(9

Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos This protein is involved inThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.