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Phospho-Bcl-2 (S87) Polyclonal Antibody, 20ul Glassware Variations in the number of

SKU: 52555304446

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Phospho-Bcl-2 (S87) Polyclonal Antibody, 20ul Glassware Variations in the number ofBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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Description

Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability

Combined with high-throughput sequencing technology

Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response

Binds to a large number of partners

Phospho-Bcl-2 (S87) Polyclonal Antibody, 20ul Glassware Variations in the number ofBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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