CD63 Polyclonal Antibody, 50ul[BT-AP01903] Shaker&Mixing Mutations in TUFM have been

Mutations in TUFM have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy

indicating that the scaffold protein can turn signaling "on" or "off" depending on the scaffold concentration

MIM 604998) (Gardner et al

or amplified in a series of tumours including anaplastic large cell lymphomas

CD63 Polyclonal Antibody, 50ul[BT-AP01903] Shaker&Mixing Mutations in TUFM have beenCASP8 (caspase 8) encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the