IRF-3 Polyclonal Antibody, 50ul[BT-AP04629] Immunoassays Mutations in this gene have

Mutations in this gene have been associated with bone marrow failure syndrome 2

This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling

LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions

This gene is one of three similar cation transporter genes located in a cluster on chromosome 6

IRF-3 Polyclonal Antibody, 50ul[BT-AP04629] Immunoassays Mutations in this gene haveIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed